Preparation
Our staff conducts comprehensive psychiatric assessment and establishes therapeutic intentions for your session.

Evidence-based ketamine-assisted psychotherapy offering rapid relief for treatment-resistant mental health conditions.
Understanding Treatment Resistance
Some individuals do not achieve adequate improvement with standard medications or therapy alone. Finding the right treatment can take time, and responses vary widely from person to person. You may go through multiple options before noticing meaningful change, and progress is not always consistent. Adjustments in approach are often needed along the way, which can add to the overall uncertainty. During this time, symptoms may continue to affect daily functioning, relationships, and overall well-being, making it difficult to feel fully like yourself.
Ketamine therapy offers a different mechanism of action compared to traditional antidepressants. Ketamine-assisted therapy combines the rapid neuroplastic effects of ketamine with integrative psychotherapy, helping you process trauma, shift perspectives, and develop new coping patterns. It is sometimes used as part of a broader treatment plan for individuals with persistent symptoms, under appropriate medical supervision.
The Science Behind the Treatment
Ketamine therapy is a medically supervised treatment using low-dose ketamine, an FDA-approved anesthetic, to reduce symptoms of depression, PTSD, anxiety, and chronic pain while supporting therapeutic insight. Ketamine has been used safely in medical settings for over 50 years and is included on the WHO List of Essential Medicines.
Ketamine acts as an NMDA receptor antagonist, affecting glutamate, the brain’s primary excitatory neurotransmitter. This can support neuroplastic changes, helping the brain form new connections. It also increases brain-derived neurotrophic factor (BDNF), which plays a role in neural growth and adaptation.
During your session, you'll recline comfortably in a therapeutic setting while our team administers ketamine via intramuscular injection or IV infusion. You'll experience altered consciousness—a dissociative state that may include visual imagery, emotional insights, and a sense of separation from ordinary concerns. Our staff member remains with you throughout, providing grounding support and therapeutic guidance. Sessions last approximately 2 hours, including the dissociative experience and integration work to process insights.
Many patients notice improvement within hours to days after the first session. A full series of 6–8 treatments over several weeks is typically recommended for initial treatment. Response varies by individual. Treatment planning and any follow-up care are personalized based on clinical response and evaluation.
Rapid, Transformative Relief
Different mechanism than traditional medications
Some individuals report early changes compared to standard treatments
Combined with guided psychotherapy
Associated with changes in brain signaling pathways
Administered in a clinical environment
Adjusted based on response and needs
Compare Your Options
| Treatment | Mechanism | Time | Results | Duration | Downtime | Best For |
|---|---|---|---|---|---|---|
| Ketamine Therapy | NMDA receptor modulation | 2 hours | Varies | Individualized | Minimal | Treatment-resistant conditions |
| Traditional Antidepressants | Neurotransmitter modulation | Daily | Varies | Ongoing | None | First-line treatment |
| Exomind TMS Therapy | Magnetic stimulation | 20–30 min/session | Varies | Multi-session | None | Non-invasive depression treatment |
Finding Your Path to Healing
Ketamine therapy may be appropriate for individuals with persistent symptoms who have not responded to standard care.
A comprehensive psychiatric and medical evaluation is required before beginning treatment to ensure safety and appropriateness.
Our staff conducts comprehensive psychiatric assessment and establishes therapeutic intentions for your session.
You'll recline in a comfortable, private therapeutic space with soft lighting, eye shades, and curated music to support your journey.
Our team administers ketamine via IM injection or IV infusion while monitoring your vital signs continuously throughout.
You'll experience approximately 2 hours of guided therapy with therapeutic support, exploring insights and processing emotions as they arise.
Following the session, our team guides integration work to anchor insights and develop actionable therapeutic strategies.
What to Know
During the ketamine-assisted therapy session, you may experience dissociation (a sense of detachment from your body), visual or auditory perceptual changes, emotional intensity, nausea (affecting 15–20% of patients), and temporary increases in blood pressure and heart rate. These effects are expected during treatment and are continuously monitored by clinical staff. They typically resolve during the recovery period after the session. Nausea can be managed with anti-nausea medication when needed.
Following treatment, some patients may experience mild fatigue, headache, or emotional sensitivity for a variable period after the session, most commonly within the same day. In rare cases, patients may experience emotionally intense or challenging psychological content during the session. When this occurs, trained clinical staff provide structured therapeutic support to ensure the experience remains safe and supported.
Ketamine was FDA-approved as an anesthetic in 1970 and has over 50 years of established medical use. While ketamine is used off-label for psychiatric conditions, all treatments are administered under medical supervision with continuous monitoring throughout the session. Vital signs, including cardiovascular measures, are tracked to ensure safety, particularly for individuals with controlled hypertension. Our team provides specialized clinical oversight in ketamine-assisted therapy. Patients are evaluated before treatment to determine appropriateness based on medical and psychiatric history, including screening for factors such as cardiovascular risk and substance use history.
Ketamine therapy in Ponte Vedra Beach typically ranges from $550-$600 per session, depending on administration method (IM vs IV), session length, and level of therapeutic support. Most patients complete an initial series of 6-8 sessions over 2-4 weeks, followed by monthly maintenance sessions. Factors affecting cost include medical monitoring requirements, integration therapy sessions, and whether treatment is combined with other modalities like psychotherapy or neurofeedback. Exact pricing will be discussed during your consultation based on your individual treatment plan.
Ketamine therapy is a self-pay service. We can provide superbills upon request that you may submit to your insurance for potential out-of-network reimbursement.
Ponte Vedra Beach's Trusted Ketamine Therapy Provider
CIIS/MAPS trained providers specializing in ketamine-assisted therapy
Our team's expertise in therapeutic integration maximizes lasting change
Continuous monitoring with PMHNP-BC and PA-C clinical supervision
Combines ketamine-assisted therapy with comprehensive psychiatric care
Discover complementary therapies designed to work alongside your treatment plan for optimal results.
Therapy, counseling, and holistic approaches for lasting emotional wellness
Non-invasive neurofeedback, brain mapping, and TMS for optimal brain health
Your Questions Answered
Ketamine-assisted therapy combines low-dose ketamine administration with therapeutic support and integration work. Unlike ketamine infusions alone, this approach uses the altered, dissociative experience as a catalyst for psychological healing and transformation, with trained therapists guiding the session and helping you process insights afterward.
When administered by trained medical professionals, ketamine therapy is very safe. We monitor vital signs continuously, screen for contraindications, and provide therapeutic support throughout. Ketamine has over 50 years of safe medical use as an anesthetic.
Most patients complete 6-8 sessions over 2-4 weeks for the initial series, with symptom relief often beginning after 1-2 treatments. Maintenance sessions are typically scheduled monthly or every 4-6 weeks to sustain benefits. Your treatment plan will be personalized based on your response.
Sessions typically range from $550-$600 per session, depending on administration method (IM vs IV), session length, and level of therapeutic support. We offer package pricing for the initial 6-8 session series. Insurance coverage is limited, but we provide documentation for out-of-network reimbursement attempts.
Ketamine therapy is most effective for treatment-resistant depression, PTSD, anxiety disorders, OCD, and chronic pain syndromes. It's particularly valuable when traditional antidepressants and therapy haven't provided adequate relief. We also offer Exomind TMS Therapy and Neurofeedback Therapy as complementary treatment options.
Sessions last approximately 2 hours. During the experience, you'll feel dissociated from ordinary reality—a dreamlike state with altered perception, emotional insights, and sometimes visual imagery. The experience is deeply personal and varies between individuals and sessions. Your provider remains with you throughout the session to provide grounding and support.
Ketamine therapy produces a temporary altered, dissociative state of consciousness, but the goal is therapeutic healing, not recreation.
Ketamine therapy for psychiatric conditions is typically not covered by insurance as it's off-label use. However, we provide documentation for out-of-network reimbursement.